The Director of the VHC
Colonel Renata J. M. Engler, MD is the Founder and Director of the Vaccine Healthcare Centers Network since September 2001. She is board certified in adult and pediatric allergy-immunology, internal medicine and has special certification in clinical laboratory immunology with over 30 years experience in military medicine to include serving as a training program director for both allergy-immunology and clinical laboratory immunology. Dr. Engler is currently a Professor in the Department of Medicine and Pediatrics at the Uniformed Services University of the Health Sciences and is a recognized expert clinical consultant in allergic and immunologic diseases, immune modulator therapy, adverse drug/vaccine reaction management, chronic fatigue syndrome and immune dysregulation disorders, insect and food hypersensitivity as well as clinical laboratory diagnostics. She has served as specialty consultant to the Office of Army Surgeon General and is currently serving as the Department of Defense Ex-Officio Representative to the National Vaccine Advisory Committee. She serves on numerous advisory groups to include the Brighton Collaboration and as a principal investigator for the Clinical Immunization Safety Assessment Centers Network supporting genetic study collaboration related to hypersensitivity myocarditis following smallpox vaccine and several other research initiatives. As part of commitment to explore all therapeutic options for complex patients who fail traditional management, particularly in the context of serious adverse events following immunizations, Dr. Engler has actively contributed to the development of clinical guidelines for use and safety surveillance of complementary and alternative medicine options with a focus on immune modulating properties of herbals that can affect vaccine responses. Other core research interests include gender differences in immune responses and vaccine associated side effect severity/risk for more serious adverse events.
References of Interest
Engler RJ, With CM, Gregory PJ, Jellin JM. Complementary and alternative medicine for the allergist-immunologist: where do I start? J Allergy Clin Immunol. 2009; 123(2):309-16. Review. PubMed PMID: 19203654.
Engler RJ, Nelson MR, Klote MM, VanRaden MJ, Chiung-Yu H, Cox NJ, Klimov A, Keitel WA, Nichol KL, Carr WW, Treanor JJ, et al. Half Dose Trivalent Inactivated Influenza Vaccine 2004-5 Compared to Full Dose: Age, Dose and Gender Effects on Immune Response. Arch Intern Med 2008; 168(22):2405-14.
Wood RA, Berger M, Dreskin SC, Setse R, Engler RJ, Dekker CL, Halsey NA. Hypersensitivity working group of the Clinical Immunization Safety Assessment (CISA) Network. Pediatrics 2008;122(3):e771-7.
Engler RJ, Klote MM, Martin BL. Optic Neuritis and Vaccination Investigation: Failure to Consider Significant Sex Differences and Multiple Vaccine Combinations. Arch Neurol 2007;64(11):1673-5.
Klote MM, Engler RJ, Martin BL, Cummings JF, Wortmann GW, Ludwig GV. Vaccinia DNA in blood after smallpox vaccination. JAMA 2006;296(11):1350-1.
Ein D, Gruchalla R, Baker JR, Bellanti JA, Engler R, Jones JF, Martin BL, Routes JM; Task Force on Smallpox Vaccination for Allergists. Pre-event smallpox vaccination and postevent exposure and disease: a report of the Joint Task Force on Smallpox Vaccination for Allergists. Ann Allergy Asthma Immunol 2005 Jan;94(1):4-7.
Wollenberg A, Engler R. Smallpox vaccination and adverse reactions to smallpox vaccine. Curr Opin Allergy Clin Immunol 2004 Aug;4(4):271-5.
Arness MK, Eckart RE, Love SS, Atwood JE, Wells TS, Engler RJ, Collins LC, Ludwig SL, Riddle JR, Grabenstein JD, Tornberg DN. Myopericarditis following smallpox vaccination. Am J Epidemiol 2004;160(7):642-51.